Estronum [Inn-Latin]
Brand names,
Estronum [Inn-Latin]
Analogs
Estronum [Inn-Latin]
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Estronum [Inn-Latin]
Chemical_Formula
C18H22O2
Estronum [Inn-Latin]
RX_link
No information avaliable
Estronum [Inn-Latin]
fda sheet
Estronum [Inn-Latin]
msds (material safety sheet)
Estronum [Inn-Latin]
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Estronum [Inn-Latin]
Molecular Weight
270.366 g/mol
Estronum [Inn-Latin]
Melting Point
254.5-256 oC
Estronum [Inn-Latin]
H2O Solubility
3 g/100mL
Estronum [Inn-Latin]
State
Solid
Estronum [Inn-Latin]
LogP
4.067
Estronum [Inn-Latin]
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Estronum [Inn-Latin]
Indication
For management of Menopausal and postmenopausal disorders
Estronum [Inn-Latin]
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Estronum [Inn-Latin]
Absorption
43%
Estronum [Inn-Latin]
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Estronum [Inn-Latin]
Patient Information
Estronum [Inn-Latin]
Organisms Affected
Humans and other mammals